Artichoke And Parmesan Tilapia is a light yet flavorful dish that combines tender tilapia fillets with a creamy artichoke and parmesan topping. The fish is baked to perfection, and the rich, savory flavors of the artichoke and parmesan mixture create a delightful contrast with the delicate fish.

Ingredients You’ll Need for Artichoke and Parmesan Tilapia
To make this artichoke and Parmesan tilapia, you’ll need a few simple ingredients that you may already have in your pantry. Here’s what you’ll need:
Tilapia fillets: Fresh or frozen tilapia fillets work perfectly for this dish. They are mild in flavor, making them ideal for the Parmesan and artichoke combination.
Parmesan cheese: Freshly grated Parmesan adds a salty, nutty flavor that enhances the tilapia’s mild taste.
Canned artichoke hearts: Artichokes add a unique, slightly tangy taste that pairs wonderfully with Parmesan.
Garlic: Minced garlic infuses the dish with a fragrant aroma and a subtle heat.
Lemon juice: A squeeze of fresh lemon juice balances the richness of the cheese and adds brightness to the dish.
Olive oil: For searing the tilapia and creating a crispy crust.
Herbs and seasonings: Fresh or dried parsley, salt, pepper, and optional red pepper flakes for an extra kick.
Tips and Tricks for Perfect Artichoke and Parmesan Tilapia
- Fresh vs Frozen Tilapia: If you’re using frozen tilapia fillets, make sure to thaw them in the refrigerator before cooking. Avoid microwaving or thawing at room temperature to preserve the fish’s texture.
- Grate Your Own Parmesan: Freshly grated Parmesan cheese will melt much better and have a stronger flavor than pre-grated cheese.
- Add a Crunch: For an extra layer of texture, you can sprinkle some breadcrumbs over the top of the artichoke and Parmesan mixture before melting it in the pan.
- Seasonings: Feel free to adjust the seasoning to your taste. A touch of red pepper flakes can add some heat, while a sprinkle of Italian seasoning will give it more depth.

Variations of Artichoke and Parmesan Tilapia
While the classic recipe is delicious on its own, there are several ways you can make this dish your own. Here are some creative variations to try:
- Swap the Fish: While tilapia is a great choice for this recipe, you can also use other mild fish like cod, haddock, or flounder.
- Add Veggies: For added flavor and nutrients, consider tossing in some spinach, sun-dried tomatoes, or roasted bell peppers into the artichoke-Parmesan mixture.
- Use Fresh Artichokes: If you’re up for a bit of extra work, use fresh artichokes instead of canned ones. Just make sure to trim and cook them before using them in the recipe.
How to Serve Artichoke and Parmesan Tilapia
This dish is versatile and can be served in several ways. Here are some ideas for pairing:
- Over Rice or Quinoa: Serve the tilapia over a bed of rice, quinoa, or cauliflower rice to make a complete meal.
- With Roasted Vegetables: Pair it with roasted vegetables such as zucchini, asparagus, or Brussels sprouts for a well-rounded dinner.
- With a Fresh Salad: A light green salad with a lemon vinaigrette complements the richness of the fish.
- On a Bed of Greens: For a low-carb option, serve the tilapia on a bed of sautéed spinach or arugula for a flavorful base.
How to Store Artichoke and Parmesan Tilapia
If you have leftovers (which might be unlikely, given how tasty this dish is!), you can store them in an airtight container in the refrigerator for up to 2-3 days. Reheat the tilapia gently in the oven or microwave. To prevent the Parmesan topping from losing its crispy texture, consider reheating the fish in a skillet over low heat, covered with a lid.
For longer storage, you can freeze the cooked fillets. Wrap them tightly in plastic wrap or aluminum foil, then place them in a freezer-safe bag. They will last up to 3 months in the freezer. Thaw the fillets in the refrigerator overnight before reheating.

Recipe FAQs
Can I make this recipe ahead of time?
Yes, you can prepare the artichoke and Parmesan mixture ahead of time and store it in the refrigerator for up to 24 hours. When you’re ready to serve, simply cook the tilapia and add the topping just before serving.
Can I use a different cheese instead of Parmesan?
While Parmesan offers a distinct flavor and texture, you can experiment with other hard cheeses like Pecorino Romano or Asiago. Just keep in mind that the flavor may differ.
How do I know if the tilapia is cooked through?
The fish is fully cooked when it flakes easily with a fork and has an internal temperature of 145°F (63°C). If you don’t have a thermometer, a visual check will also tell you that the fish is opaque throughout.
What can I serve with this dish for a low-carb meal?
To keep things low-carb, try serving the tilapia with a side of sautéed greens like spinach or kale, roasted cauliflower, or even a simple cucumber salad.
Artichoke And Parmesan Tilapia

Artichoke And Parmesan Tilapia is a light yet flavorful dish that combines tender tilapia fillets with a creamy artichoke and parmesan topping. The fish is baked to perfection, and the rich, savory flavors of the artichoke and parmesan mixture create a delightful contrast with the delicate fish.
Ingredients
- 1 lb tilapia (cut into 4 fillets)
- 6 oz artichoke hearts (rinsed and drained)
- ¼ cup whole wheat breadcrumbs
- ¼ cup grated Parmesan cheese
- 1 tsp fresh lemon juice
- 1 tsp dried oregano
- Salt and pepper (to taste)
Instructions
- Preheat your oven to 375°F and line a baking sheet with parchment paper. Lightly mist with olive oil or non-fat cooking spray.
- Pat the tilapia fillets dry, season with salt and pepper, and place them on the baking sheet.
- In a bowl, mix the artichoke hearts, breadcrumbs, Parmesan, oregano, and lemon juice.
- Spoon the artichoke mixture over each fillet, then bake for 15-20 minutes, or until the fish is cooked through and flakes easily.
Nutrition Information
Yield
4Serving Size
1Amount Per Serving Calories 263Total Fat 6gSaturated Fat 2gTrans Fat 0gUnsaturated Fat 3gCholesterol 70mgSodium 328mgCarbohydrates 20gFiber 4gSugar 1gProtein 36g
dinnerbytes.com, occasionally offers nutritional information for recipes contained on this site. This information is provided as a courtesy and is an estimate only. This information comes from online calculators. Although dinnerbytes.com attempts to provide accurate nutritional information, these figures are only estimates.

Final outcome
Artichoke and Parmesan Tilapia is a simple yet luxurious dish that combines fresh, mild fish with savory cheese and flavorful artichokes. Whether you serve it with a side of vegetables, over rice, or on its own, this recipe is sure to become a favorite. With its rich taste, light texture, and nutritional benefits, it’s a fantastic option for anyone looking to enjoy a healthy and satisfying meal.
Try these other tilapia recipes: